Note of genetic data generation
Reference: An Alphabetic List of Genetic Analysis Software http://linkage.rockefeller.edu/soft/list1.html
這個網站依照英文字母排序，依序列出了很多遺傳分析軟體的連結及這些軟體的基本資訊，是蠻實用的網站。
Generate family data
1. SimPed
Name
SimPed
Authors
Suzanne M. Leal, Kai Yan, and Bertram Muller-Myhsok
Reference
SimPed: A simulation program to generate haplotype and genotype data for pedigree structure , Human Heredity (2005), 60: 119-122
Web
http://www.hgsc.bcm.tmc.edu/genemapping/
Source code
C language
OS
Windows, Linux, Unix
Data type
Family haplotype/ genotype data
Descriptions
SimPed is a simulation program that quickly generates haplotype and/ or genotype data unconditional on the disease/ quantitative trait status for pedigrees of virtually any size and complexity. The program can generate data for a large number of either diallelic or multiallelic marker loci (>20000 loci). Haplotypes and/or genotypes are generated using user specified genetic map distances and haplotypes and/or allele frequencies.
Limitation
SimPed only generate data under the null hypothesis. The data generated by the program only can be used for evaluation type I error and empirical p value.
